Mechanism of action of Pseudomonas aeruginosa exotoxin Aiadenosine diphosphate-ribosylation of mammalian elongation factor 2 in vitro and in vivo.

Previous studies showed that Pseudomonas aeruginosa exotoxin A (PA toxin) catalyzes nicotinamide adenine dinucleotide (NAD)-dependent inhibition of protein synthesis in a rabbit reticulocyte lysate and transfer of radioactivity from [14C]adenine-labeled NAD to a protein having the same molecular wei...

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Detalles Bibliográficos
Main Authors: Iglewski, B H, Liu, P V, Kabat, D
Formato: Artigo
Idioma:Inglês
Publicado: 1977
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC421339/
https://ncbi.nlm.nih.gov/pubmed/188760
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