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A Root-Expressed l-Phenylalanine:4-Hydroxyphenylpyruvate Aminotransferase Is Required for Tropane Alkaloid Biosynthesis in Atropa belladonna

The tropane alkaloids, hyoscyamine and scopolamine, are medicinal compounds that are the active components of several therapeutics. Hyoscyamine and scopolamine are synthesized in the roots of specific genera of the Solanaceae in a multistep pathway that is only partially elucidated. To facilitate gr...

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Autors principals: Bedewitz, Matthew A., Góngora-Castillo, Elsa, Uebler, Joseph B., Gonzales-Vigil, Eliana, Wiegert-Rininger, Krystle E., Childs, Kevin L., Hamilton, John P., Vaillancourt, Brieanne, Yeo, Yun-Soo, Chappell, Joseph, DellaPenna, Dean, Jones, A. Daniel, Buell, C. Robin, Barry, Cornelius S.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Plant Biologists 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4213168/
https://ncbi.nlm.nih.gov/pubmed/25228340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1105/tpc.114.130534
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