A Root-Expressed l-Phenylalanine:4-Hydroxyphenylpyruvate Aminotransferase Is Required for Tropane Alkaloid Biosynthesis in Atropa belladonna

The tropane alkaloids, hyoscyamine and scopolamine, are medicinal compounds that are the active components of several therapeutics. Hyoscyamine and scopolamine are synthesized in the roots of specific genera of the Solanaceae in a multistep pathway that is only partially elucidated. To facilitate gr...

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Main Authors: Bedewitz, Matthew A., Góngora-Castillo, Elsa, Uebler, Joseph B., Gonzales-Vigil, Eliana, Wiegert-Rininger, Krystle E., Childs, Kevin L., Hamilton, John P., Vaillancourt, Brieanne, Yeo, Yun-Soo, Chappell, Joseph, DellaPenna, Dean, Jones, A. Daniel, Buell, C. Robin, Barry, Cornelius S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Plant Biologists 2014
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4213168/
https://ncbi.nlm.nih.gov/pubmed/25228340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1105/tpc.114.130534
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