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Structural Basis of Substrate Selectivity of E. coli Prolidase

Prolidases, metalloproteases that catalyze the cleavage of Xaa-Pro dipeptides, are conserved enzymes found in prokaryotes and eukaryotes. In humans, prolidase is crucial for the recycling of collagen. To further characterize the essential elements of this enzyme, we utilized the Escherichia coli pro...

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Detalhes bibliográficos
Main Authors: Weaver, Jeremy, Watts, Tylan, Li, Pingwei, Rye, Hays S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4213023/
https://ncbi.nlm.nih.gov/pubmed/25354344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0111531
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