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Structural Basis of Substrate Selectivity of E. coli Prolidase
Prolidases, metalloproteases that catalyze the cleavage of Xaa-Pro dipeptides, are conserved enzymes found in prokaryotes and eukaryotes. In humans, prolidase is crucial for the recycling of collagen. To further characterize the essential elements of this enzyme, we utilized the Escherichia coli pro...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Public Library of Science
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4213023/ https://ncbi.nlm.nih.gov/pubmed/25354344 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0111531 |
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