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Expression and Localization of P-Glycoprotein, Multidrug Resistance Protein 4, and Breast Cancer Resistance Protein in the Female Lower Genital Tract of Human and Pigtailed Macaque

Antiretroviral drug absorption and disposition in cervicovaginal tissue is important for the effectiveness of vaginally or orally administered drug products in preexposure prophylaxis (PrEP) of HIV-1 sexual transmission to women. Therefore, it is imperative to understand critical determinants of cer...

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Bibliographic Details
Main Authors: Zhou, Tian, Hu, Minlu, Pearlman, Andrew, Patton, Dorothy, Rohan, Lisa
Format: Artigo
Language:Inglês
Published: Mary Ann Liebert, Inc. 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4212939/
https://ncbi.nlm.nih.gov/pubmed/24803409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/aid.2013.0281
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