Serum α-hydroxybutyrate (α-HB) predicts elevated 1 h glucose levels and early-phase β-cell dysfunction during OGTT

OBJECTIVE: Serum α-hydroxybutyrate (α-HB) is elevated in insulin resistance and diabetes. We tested the hypothesis that the α-HB level predicts abnormal 1 h glucose levels and β-cell dysfunction inferred from plasma insulin kinetics during a 75 g oral glucose tolerance test (OGTT). RESEARCH DESIGN A...

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Autori principali: Varvel, Stephen A, Pottala, James V, Thiselton, Dawn L, Caffrey, Rebecca, Dall, Tara, Sasinowski, Maciek, McConnell, Joseph P, Warnick, G Russell, Voros, Szilard, Graham, Timothy E
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMJ Publishing Group 2014
Soggetti:
Epidemiology/Health service research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4212560/
https://ncbi.nlm.nih.gov/pubmed/25452875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjdrc-2014-000038
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