Antitumor Effects of Flavopiridol on Human Uterine Leiomyoma In Vitro and in a Xenograft Model

Dysregulated cyclin-dependent kinases (CDKs) are considered a potential target for cancer therapy. Flavopiridol is a potent CDK inhibitor. In this study, the antiproliferative effect of the flavonoid compound flavopiridol and its mechanism in human uterine leiomyoma cells were investigated. The pres...

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Detalhes bibliográficos
Main Authors: Lee, Hyun-Gyo, Baek, Jong-Woo, Shin, So-Jin, Kwon, Sang-Hoon, Cha, Soon-Do, Park, Won-Jin, Chung, Rosa, Choi, Eun-Som, Lee, Gun-Ho, Cho, Chi-Heum
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2014
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4212340/
https://ncbi.nlm.nih.gov/pubmed/24572052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1933719114525266
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