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Claudin-4 controls the receptor tyrosine kinase EphA2 pro-oncogenic switch through β-catenin
BACKGROUND: The EphA2 receptor, which is expressed in many types of cancer, is activated by two different mechanisms. Activation by engagement with one of its ephrin ligands is anti-oncogenic whereas phosphorylation of S897 by AKT increases migration, invasion and metastasis. Down-regulation of clau...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4212103/ https://ncbi.nlm.nih.gov/pubmed/25344320 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-014-0059-5 |
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