TLR Signals Induce Phagosomal MHC-I Delivery from the Endosomal Recycling Compartment to Allow Cross-Presentation

Adaptation of the endoplasmic reticulum (ER) pathway for MHC class I (MHC-I) presentation in dendritic cells enables cross-presentation of peptides derived from phagocytosed microbes, infected cells, or tumor cells to CD8 T cells. How these peptides intersect with MHC-I molecules remains poorly unde...

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Detalhes bibliográficos
Main Authors: Nair-Gupta, Priyanka, Baccarini, Alessia, Tung, Navpreet, Seyffer, Fabian, Florey, Oliver, Huang, Yunjie, Huang, Meenakshi, Overholtzer, Michael, Roche, Paul A., Tampé, Robert, Brown, Brian D., Amsen, Derk, Whiteheart, Sidney W., Blander, J. Magarian
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4212008/
https://ncbi.nlm.nih.gov/pubmed/25083866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.04.054
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