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Targeted therapy with MXD3 siRNA, anti-CD22 antibody and nanoparticles for precursor B-cell acute lymphoblastic leukaemia

Conventional chemotherapy for precursor B-cell (preB) acute lymphoblastic leukaemia (ALL) has limitations that could be overcome by targeted therapy. Previously, we discovered a potential therapeutic molecular target, MDX3 (MAX dimerization protein 3), in preB ALL. In this study, we hypothesize that...

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Detalhes bibliográficos
Main Authors: Satake, Noriko, Duong, Connie, Chen, Cathy, Barisone, Gustavo A., Diaz, Elva, Tuscano, Joseph, Rocke, David M., Nolta, Jan, Nitin, Nitin
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4212003/
https://ncbi.nlm.nih.gov/pubmed/25196579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bjh.13066
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