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Alcohol Alters Insulin-Like Growth Factor-1-Induced Transforming Growth Factor-ß1 Synthesis in the Medial Basal Hypothalamus of the Prepubertal Female Rat

OBJECTIVE: Insulin-like growth factor-1 (IGF-1) and transforming growth factor ß1 (TGFß1) are produced in hypothalamic astrocytes and facilitate luteinizing hormone-releasing hormone (LHRH) secretion. IGF-1 stimulates release by acting directly on the LHRH nerve terminals and both peptides act indir...

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Detalhes bibliográficos
Main Authors: Hiney, Jill K., Srivastava, Vinod K., Volz, Claire E., Dees, William L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4211981/
https://ncbi.nlm.nih.gov/pubmed/25335926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acer.12534
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