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Phase II trial of paclitaxel, 13-cis retinoic acid and interferon alfa-2b in the treatment of advanced stage or recurrent cervical cancer

OBJECTIVE: Overexpression of bcl-2 is a mechanism of drug resistance in cervical cancer. Agents that downregulate bcl-2 may decrease tumor cell threshold and sensitize tumor cells to chemotherapy. The objective of this multi-institutional phase II trial was to evaluate the efficacy and toxicity of p...

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Detalhes bibliográficos
Main Authors: Song, Mihae, DiPaola, Robert S., Cracchiolo, Bernadette M., Gibbon, Darlene G., Hellmann, Mira, Nieves-Neira, Wilberto, Vaidya, Ami, Wagreich, Allison R., Shih, Weichung J., Rodriguez-Rodriguez, Lorna
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4211961/
https://ncbi.nlm.nih.gov/pubmed/25304678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/IGC.0000000000000258
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