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The sustained-release behavior and in vitro and in vivo transfection of pEGFP-loaded core-shell-structured chitosan-based composite particles

Novel submicron core-shell-structured chitosan-based composite particles encapsulated with enhanced green fluorescent protein plasmids (pEGFP) were prepared by complex coacervation method. The core was pEGFP-loaded thiolated N-alkylated chitosan (TACS) and the shell was pH- and temperature-responsiv...

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Détails bibliographiques
Auteurs principaux: Wang, Yun, Lin, Fu-xing, Zhao, Yu, Wang, Mo-zhen, Ge, Xue-wu, Gong, Zheng-xing, Bao, Dan-dan, Gu, Yu-fang
Format: Artigo
Langue:Inglês
Publié: Dove Medical Press 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4211910/
https://ncbi.nlm.nih.gov/pubmed/25364253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S58104
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