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Cannabinoid Type 1 and Type 2 Receptor Antagonists Prevent Attenuation of Serotonin-Induced Reflex Apneas by Dronabinol in Sprague-Dawley Rats

The prevalence of obstructive sleep apnea (OSA) in Americans is 9% and increasing. Increased afferent vagal activation may predispose to OSA by reducing upper airway muscle activation/patency and disrupting respiratory rhythmogenesis. Vagal afferent neurons are inhibited by cannabinoid type 1 (CB(1)...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Calik, Michael W., Carley, David W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4211887/
https://ncbi.nlm.nih.gov/pubmed/25350456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0111412
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