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Engineering microorganisms based on molecular evolutionary analysis: a succinate production case study

Evolution has resulted in thousands of species possessing similar metabolic enzymes with identical functions that are, however, regulated by different mechanisms. It is thus difficult to select optimal gene to engineer novel or manipulated metabolic pathways. Here, we tested the ability of molecular...

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Autores principales: Ma, Xianghui, Zhang, Xinbo, Wang, Baiyun, Mao, Yufeng, Wang, Zhiwen, Chen, Tao, Zhao, Xueming
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Publishing Ltd 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4211721/
https://ncbi.nlm.nih.gov/pubmed/25469170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/eva.12186
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