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The Functions of Crucial Cysteine Residues in the Arsenite Methylation Catalyzed by Recombinant Human Arsenic (III) Methyltransferase

Arsenic (III) methyltransferase (AS3MT) is a cysteine (Cys)-rich enzyme that catalyzes the biomethylation of arsenic. To investigate how these crucial Cys residues promote catalysis, we used matrix-assisted laser desorption ionization-time of flight-mass spectrometry (MALDI-TOF-MS) to analyze Cys re...

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Détails bibliographiques
Auteurs principaux: Wang, Shuping, Geng, Zhirong, Shi, Nan, Li, Xiangli, Wang, Zhilin
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4211708/
https://ncbi.nlm.nih.gov/pubmed/25349987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0110924
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