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Activation of botulinum toxins in the absence of nicking.

The derivative toxins purified from cultures of proteolytic strains of Clostridium botulinum types A and F were found to have been only partially nicked but were fully activated. Trypsinization of C. botulinum type B derivative toxin at pH 6.0 resulted in simultaneous activation and nicking, whereas...

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Bibliografiske detaljer
Udgivet i:Infect Immun
Principais autores: Ohishi, I, Sakaguchi, G
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1977
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC421135/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/19360/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.17.2.402-407.1977
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