Activation of botulinum toxins in the absence of nicking.
The derivative toxins purified from cultures of proteolytic strains of Clostridium botulinum types A and F were found to have been only partially nicked but were fully activated. Trypsinization of C. botulinum type B derivative toxin at pH 6.0 resulted in simultaneous activation and nicking, whereas...
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| Udgivet i: | Infect Immun |
|---|---|
| Principais autores: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology (ASM)
1977
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC421135/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/19360/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.17.2.402-407.1977 |
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