Diethylcarbamazine Reduces Chronic Inflammation and Fibrosis in Carbon Tetrachloride- (CCl(4)-) Induced Liver Injury in Mice

This study investigated the anti-inflammatory effects of DEC on the CCl(4)-induced hepatotoxicity in C57BL/6 mice. Chronic inflammation was induced by i.p. administration of CCl(4) 0.5 μL/g of body weight through two injections a week for 6 weeks. DEC (50 mg/kg) was administered by gavage for 12 day...

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Hauptverfasser: Rocha, Sura Wanessa Santos, de França, Maria Eduarda Rocha, Rodrigues, Gabriel Barros, Barbosa, Karla Patrícia Sousa, Nunes, Ana Karolina Santana, Pastor, André Filipe, Oliveira, Anne Gabrielle Vasconcelos, Oliveira, Wilma Helena, Luna, Rayana Leal Almeida, Peixoto, Christina Alves
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi Publishing Corporation 2014
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4211150/
https://ncbi.nlm.nih.gov/pubmed/25374445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/696383
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