Extensive stage-regulation of translation revealed by ribosome profiling of Trypanosoma brucei

BACKGROUND: Trypanosoma brucei subspecies infect humans and animals in sub-Saharan Africa. This early diverging eukaryote shows many novel features in basic biological processes, including the use of polycistronic transcription to generate all protein-coding mRNAs. Therefore we hypothesized that tra...

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Hauptverfasser: Jensen, Bryan C, Ramasamy, Gowthaman, Vasconcelos, Elton J R, Ingolia, Nicholas T, Myler, Peter J, Parsons, Marilyn
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2014
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4210626/
https://ncbi.nlm.nih.gov/pubmed/25331479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-911
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