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GLUT-1 expression is largely unrelated to both hypoxia and the Warburg phenotype in squamous cell carcinomas of the vulva

BACKGROUND: Strongly increased uptake of glucose is a hallmark of solid malignant tumors. This phenotype can be triggered by hypoxia-induced gene expression changes or can occur independently of hypoxia as a consequence of malignant transformation itself, and is often referred to as the Warburg effe...

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Detalhes bibliográficos
Main Authors: Mayer, Arnulf, Schmidt, Marcus, Seeger, Alexander, Serras, André Franke, Vaupel, Peter, Schmidberger, Heinz
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4210616/
https://ncbi.nlm.nih.gov/pubmed/25306097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-760
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