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Controlled delivery of BID protein fused with TAT peptide sensitizes cancer cells to apoptosis

BACKGROUND: Low cellular level of BID is critical for viability of numerous cancer cells. Sensitization of cells to anticancer agents by BID overexpression from adenovirus or pcDNA vectors is a proposed strategy for cancer therapy; however it does not provide any stringent control of cellular level...

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Detalhes bibliográficos
Main Authors: Orzechowska, Emilia Joanna, Kozlowska, Ewa, Czubaty, Alicja, Kozlowski, Piotr, Staron, Krzysztof, Trzcinska-Danielewicz, Joanna
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4210496/
https://ncbi.nlm.nih.gov/pubmed/25326334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-771
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