Role of protein kinase R in the killing of Leishmania major by macrophages in response to neutrophil elastase and TLR4 via TNFα and IFNβ

In cutaneous leishmaniasis, Leishmania amazonensis activates macrophage double-stranded, RNA-activated protein kinase R (PKR) to promote parasite growth. In our study, Leishmania major grew normally in RAW cells, RAW-expressing dominant-negative PKR (PKR-DN) cells, and macrophages of PKR-knockout mi...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Faria, Marilia S., Calegari-Silva, Tereza C., de Carvalho Vivarini, Aislan, Mottram, Jeremy C., Lopes, Ulisses Gazos, Lima, Ana Paula C. A.
Format: Artigo
Idioma:Inglês
Publicat: Federation of American Societies for Experimental Biology 2014
Matèries:
Research Communications
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4210457/
https://ncbi.nlm.nih.gov/pubmed/24732131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.13-245126
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars