Interdomain allosteric regulation of Polo kinase by Aurora B and Map205 is required for cytokinesis

Drosophila melanogaster Polo and its human orthologue Polo-like kinase 1 fulfill essential roles during cell division. Members of the Polo-like kinase (Plk) family contain an N-terminal kinase domain (KD) and a C-terminal Polo-Box domain (PBD), which mediates protein interactions. How Plks are regul...

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Hlavní autoři: Kachaner, David, Pinson, Xavier, El Kadhi, Khaled Ben, Normandin, Karine, Talje, Lama, Lavoie, Hugo, Lépine, Guillaume, Carréno, Sébastien, Kwok, Benjamin H., Hickson, Gilles R., Archambault, Vincent
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2014
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Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4210448/
https://ncbi.nlm.nih.gov/pubmed/25332165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201408081
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