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Acinus integrates AKT1 and subapoptotic caspase activities to regulate basal autophagy

How cellular stresses up-regulate autophagy is not fully understood. One potential regulator is the Drosophila melanogaster protein Acinus (Acn), which is necessary for autophagy induction and triggers excess autophagy when overexpressed. We show that cell type–specific regulation of Acn depends on...

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Bibliografische gegevens
Hoofdauteurs: Nandi, Nilay, Tyra, Lauren K., Stenesen, Drew, Krämer, Helmut
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Rockefeller University Press 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4210446/
https://ncbi.nlm.nih.gov/pubmed/25332163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201404028
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