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Evidence for a mouse pathogenicity locus in certain temperature-sensitive mutants of foot-and-mouth disease virus.

Serial tissue culture passaging of three foot-and-mouth disease temperature-sensitive mutants demonstrated the stability of their temperature sensitivity and mouse avirulence characteristics. Recovery of mouse-virulent temperature-sensitive viruses after passage of the mutants in mice suggested that...

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Bibliographic Details
Main Author: Richmond, J Y
Format: Artigo
Language:Inglês
Published: 1977
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC421037/
https://ncbi.nlm.nih.gov/pubmed/197007
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