Rat N-ERC/Mesothelin as a Marker for In Vivo Screening of Drugs against Pancreas Cancer

Pancreatic ductal adenocarcinoma (PDA) is a highly lethal disease, which is usually diagnosed in an advanced stage. We have established transgenic rats carrying a mutated K-ras gene controlled by Cre/loxP activation. The animals develop PDA which is histopathologically similar to that in humans. Pre...

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Detalhes bibliográficos
Main Authors: Fukamachi, Katsumi, Iigo, Masaaki, Hagiwara, Yoshiaki, Shibata, Koji, Futakuchi, Mitsuru, Alexander, David B., Hino, Okio, Suzui, Masumi, Tsuda, Hiroyuki
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4210215/
https://ncbi.nlm.nih.gov/pubmed/25347530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0111481
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