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A General MRI-CEST Ratiometric Approach for pH Imaging: Demonstration of in Vivo pH Mapping with Iobitridol

[Image: see text] Chemical exchange saturation transfer (CEST) is a novel contrast mechanism for magnetic resonance imaging (MRI). CEST MRI selectively saturates exchangeable protons that are transferred to MRI-detectable bulk water signal. MRI-CEST (pH)-responsive agents are probes able to map pH i...

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Bibliographische Detailangaben
Hauptverfasser: Longo, Dario L., Sun, Phillip Zhe, Consolino, Lorena, Michelotti, Filippo C., Uggeri, Fulvio, Aime, Silvio
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Chemical Society 2014
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4210149/
https://ncbi.nlm.nih.gov/pubmed/25238643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja5059313
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