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Sequence-Specific Dimerization of a Transmembrane Helix in Amphipol A8-35

As traditional detergents might destabilize or even denature membrane proteins, amphiphilic polymers have moved into the focus of membrane-protein research in recent years. Thus far, Amphipols are the best studied amphiphilic copolymers, having a hydrophilic backbone with short hydrophobic chains. H...

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Autori principali: Stangl, Michael, Unger, Sebastian, Keller, Sandro, Schneider, Dirk
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4210147/
https://ncbi.nlm.nih.gov/pubmed/25347769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0110970
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