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The HBx Oncoprotein of Hepatitis B Virus Deregulates the Cell Cycle by Promoting the Intracellular Accumulation and Re-Compartmentalization of the Cellular Deubiquitinase USP37

The HBx oncoprotein of hepatitis B Virus has been accredited as one of the protagonists in driving hepatocarcinogenesis. HBx exerts its influence over the cell cycle progression by potentiating the activity of cyclin A/E-CDK2 complex, the Cyclin A partner of which is a well-known target of cellular...

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מידע ביבליוגרפי
Main Authors: Saxena, Nehul, Kumar, Vijay
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2014
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4210131/
https://ncbi.nlm.nih.gov/pubmed/25347529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0111256
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