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PICK1 links Argonaute 2 to endosomes in neuronal dendrites and regulates miRNA activity

MicroRNAs fine-tune gene expression by inhibiting the translation of mRNA targets. Argonaute (Ago) proteins are critical mediators of microRNA-induced post-transcriptional silencing and have been shown to associate with endosomal compartments, but the molecular mechanisms that underlie this process...

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Autors principals: Antoniou, Anna, Baptista, Marcio, Carney, Nicholas, Hanley, Jonathan G
Format: Artigo
Idioma:Inglês
Publicat: BlackWell Publishing Ltd 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4210090/
https://ncbi.nlm.nih.gov/pubmed/24723684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/embr.201337631
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