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The antiproliferative activity of c-myb and c-myc antisense oligonucleotides in smooth muscle cells is caused by a nonantisense mechanism.

Smooth muscle cell (SMC) proliferation is thought to play a major role in vascular restenosis after angioplasty and is a serious complication of the procedure. Developing antisense (AS) oligonucleotides as therapeutics is attractive because of the potentially high specificity of binding to their tar...

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Dettagli Bibliografici
Autori principali: Burgess, T L, Fisher, E F, Ross, S L, Bready, J V, Qian, Y X, Bayewitch, L A, Cohen, A M, Herrera, C J, Hu, S S, Kramer, T B
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1995
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC42100/
https://ncbi.nlm.nih.gov/pubmed/7732029
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