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Softening the Rule of Five—where to draw the line?()

In order to improve the discovery and development of new drugs, a broad effort is being made to assess the ‘drug-like’ properties of molecules in early stages of the discovery-research process. Although there are numerous approaches to this problem, perhaps the simplest and most widespread one is th...

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Main Authors: Petit, Joachim, Meurice, Nathalie, Kaiser, Christine, Maggiora, Gerald
Formato: Artigo
Idioma:Inglês
Publicado: 2011
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4209914/
https://ncbi.nlm.nih.gov/pubmed/22222160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2011.11.064
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