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Three Decades of Research on O-GlcNAcylation – A Major Nutrient Sensor That Regulates Signaling, Transcription and Cellular Metabolism

Even though the dynamic modification of polypeptides by the monosaccharide, O-linked N-acetylglucosamine (O-GlcNAcylation) was discovered over 30 years ago, its physiological significance as a major nutrient sensor that regulates myriad cellular processes has only recently been more widely appreciat...

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Detalhes bibliográficos
Autor principal: Hart, Gerald W.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4209869/
https://ncbi.nlm.nih.gov/pubmed/25386167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2014.00183
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