Freeze-Drying of Plant Tissue Containing HBV Surface Antigen for the Oral Vaccine against Hepatitis B

The aim of this study was to develop a freeze-drying protocol facilitating successful processing of plant material containing the small surface antigen of hepatitis B virus (S-HBsAg) while preserving its VLP structure and immunogenicity. Freeze-drying of the antigen in lettuce leaf tissue, without a...

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Main Authors: Czyż, Marcin, Dembczyński, Radosław, Marecik, Roman, Wojas-Turek, Justyna, Milczarek, Magdalena, Pajtasz-Piasecka, Elżbieta, Wietrzyk, Joanna, Pniewski, Tomasz
Formato: Artigo
Idioma:Inglês
Publicado: Hindawi Publishing Corporation 2014
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4209752/
https://ncbi.nlm.nih.gov/pubmed/25371900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/485689
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