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A single phosphotyrosine residue of the prolactin receptor is responsible for activation of gene transcription.

Members of the cytokine/growth hormone/prolactin (PRL) receptor superfamily are associated with cytoplasmic tyrosine kinases of the Jak family. For the PRL receptor (PRLR), after PRL stimulation, both the kinase Jak2 and the receptor undergo tyrosine phosphorylation. To assess the role of tyrosine p...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Lebrun, J J, Ali, S, Goffin, V, Ullrich, A, Kelly, P A
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1995
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42096/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7537382/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.9.4031
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