Control of CXCR2 activity through its ubiquitination on K327 residue

BACKGROUND: The interleukin-8 chemokine (IL-8) G-protein coupled receptor CXCR2 governs pro-inflammatory and pro-angiogenic responses in leukocytes and endothelial cells. At a molecular standpoint, CXCR2 is widely reported to operate through calcium flux, phosphoinoisitide 3 kinase (PI3K) and mitoge...

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Main Authors: Leclair, Héloise M, Dubois, Sonia M, Azzi, Sandy, Dwyer, Julie, Bidère, Nicolas, Gavard, Julie
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2014
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4209453/
https://ncbi.nlm.nih.gov/pubmed/25339290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12860-014-0038-0
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