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Development of a purified cholera toxoid. III. Refinements in purification of toxin and methods for the determination of residual somatic antigen.

The addition of an ultrafiltration step to the purification procedures previously described for cholera toxin (Rappaport et al., (1974) permitted the preparation of highly purified antigenic toxoids essentially free of somatic antigen(s). The purity of such toxoids is established: (i) by the absence...

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Main Authors: Rappaport, R S, Pierzchala, W A, Bonde, G, McCann, T, Rubin, B A
格式: Artigo
語言:Inglês
出版: 1976
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC420941/
https://ncbi.nlm.nih.gov/pubmed/823117
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