Mutagenicity of furan in female Big Blue B6C3F1 mice

Furan is an abundant food and environmental contaminant that is a potent liver carcinogen in rodent models. To determine if furan is genotoxic in vivo, female B6C3F1 Big Blue transgenic mice were treated with 15 mg/kg bw furan by gavage 5 days a week for 6 weeks, or once weekly for 3 weeks. Liver cI...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Terrell, Ashley N., Huynh, Mailee, Grill, Alex E., Kovi, Ramesh C., O’Sullivan, M. Gerard, Guttenplan, Joseph B., Ho, Yen-Yi, Peterson, Lisa A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2014
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4209239/
https://ncbi.nlm.nih.gov/pubmed/25344163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrgentox.2014.04.024
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