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Preclinical validation of interleukin 6 as a therapeutic target in multiple myeloma

Studies on the biologic and molecular genetic underpinnings of multiple myeloma (MM) have identified the pleiotropic, pro-inflammatory cytokine, interleukin-6 (IL-6), as a factor crucial to the growth, proliferation and survival of myeloma cells. IL-6 is also a potent stimulator of osteoclastogenesi...

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Detalhes bibliográficos
Main Authors: Rosean, Timothy R., Tompkins, Van S., Tricot, Guido, Holman, Carol J., Olivier, Alicia K., Zhan, Fenghuang, Janz, Siegfried
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4209159/
https://ncbi.nlm.nih.gov/pubmed/24845460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12026-014-8528-x
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