LPS Nephropathy in Mice Is Ameliorated by IL-2 Independently of Regulatory T Cells Activity

Immunosuppressive regulatory T cells (Tregs) have been hypothesized to exert a protective role in animal models of spontaneous (Buffalo/Mna) and/or drug induced (Adriamycin) nephrotic syndrome. In this study, we thought to define whether Tregs can modify the outcome of LPS nephropathy utilizing IL-2...

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Bibliografski detalji
Glavni autori: Bertelli, Roberta, Di Donato, Armando, Cioni, Michela, Grassi, Fabio, Ikehata, Masami, Bonanni, Alice, Rastaldi, Maria Pia, Ghiggeri, Gian Marco
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4208845/
https://ncbi.nlm.nih.gov/pubmed/25343479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0111285
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