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The Dual Role of Scavenger Receptor Class A in Development of Diabetes in Autoimmune NOD Mice

Human type 1 diabetes is an autoimmune disease that results from the autoreactive destruction of pancreatic β cells by T cells. Antigen presenting cells including dendritic cells and macrophages are required to activate and suppress antigen-specific T cells. It has been suggested that antigen uptake...

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Détails bibliographiques
Auteurs principaux: Shimizu, Mami, Yasuda, Hisafumi, Hara, Kenta, Takahashi, Kazuma, Nagata, Masao, Yokono, Koichi
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4208757/
https://ncbi.nlm.nih.gov/pubmed/25343451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0109531
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