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A Randomized, Double-Blind, Placebo-Controlled Phase II Clinical Trial of Lovastatin for Various Endpoints of Melanoma Pathobiology

Based on large cardiovascular clinical trials of lipid lowering agents that showed a considerable decrease in incidence of primary melanomas in the active agent arm, we have carried out a randomized, double-blind clinical trial examining the impact of lovastatin on various biomarkers of melanoma pat...

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Main Authors: Linden, Kenneth G., Leachman, Sancy A., Zager, Jonathan S., Jakowatz, James G., Viner, Jaye L., McLaren, Christine E., Barr, Ronald J., Carpenter, Philip M., Chen, Wen-Pin, Elmets, Craig A., Tangrea, Joseph A., Lim, Sung-Jig, Cochran, Alistair J., Meyskens, Frank L.
格式: Artigo
語言:Inglês
出版: 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4208700/
https://ncbi.nlm.nih.gov/pubmed/24614012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-13-0189
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