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Quantitative Evaluation of DNA Dissociation from Liposome Carriers and DNA Escape from Endosomes During Lipid-Mediated Gene Delivery

Nonviral vectors are highly attractive for gene therapy from a clinical point of view, and cationic lipid nanoparticles in particular have generated considerable interest. However, despite considerable recent advances, problems associated with low transfection efficiencies remain to be resolved to f...

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Detalhes bibliográficos
Main Authors: Magalhães, Salomé, Duarte, Sofia, Monteiro, Gabriel A., Fernandes, Fábio
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4208615/
https://ncbi.nlm.nih.gov/pubmed/25285806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hgtb.2014.080
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