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Amide Coupling Reaction for the Synthesis of Bispyridine-based Ligands and Their Complexation to Platinum as Dinuclear Anticancer Agents

Amide coupling reactions can be used to synthesize bispyridine-based ligands for use as bridging linkers in multinuclear platinum anticancer drugs. Isonicotinic acid, or its derivatives, are coupled to variable length diaminoalkane chains under an inert atmosphere in anhydrous DMF or DMSO with the u...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Apps, Michael G., Johnson, Ben W., Sutcliffe, Oliver B., Brown, Sarah D., Wheate, Nial J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MyJove Corporation 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4208593/
https://ncbi.nlm.nih.gov/pubmed/24893964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/51740
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