Midbody accumulation through evasion of autophagy contributes to cellular reprogramming and tumorigenicity

The midbody (MB) is a singular organelle formed between daughter cells during cytokinesis and required for their final separation. MBs persist in cells long after division as midbody derivatives (MB(d)s), but their fate is unclear. Here we show that MB(d)s are inherited asymmetrically by the daughte...

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Hauptverfasser: Kuo, Tse-Chun, Chen, Chun-Ting, Baron, Desiree, Onder, Tamer T., Loewer, Sabine, Almeida, Sandra, Weismann, Cara, Xu, Ping, Houghton, Jean-Marie, Gao, Fen-Biao, Daley, George Q., Doxsey, Stephen
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4208311/
https://ncbi.nlm.nih.gov/pubmed/21909099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2332
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