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Necrostatin-1 protects against reactive oxygen species (ROS)-induced hepatotoxicity in acetaminophen-induced acute liver failure

Excessive acetaminophen (APAP) use is one of the most common causes of acute liver failure. Various types of cell death in the damaged liver are linked to APAP-induced hepatotoxicity, and, of these, necrotic cell death of hepatocytes has been shown to be involved in disease pathogenesis. Until recen...

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Autors principals: Takemoto, Kenji, Hatano, Etsuro, Iwaisako, Keiko, Takeiri, Masatoshi, Noma, Naruto, Ohmae, Saori, Toriguchi, Kan, Tanabe, Kazutaka, Tanaka, Hirokazu, Seo, Satoru, Taura, Kojiro, Machida, Keigo, Takeda, Norihiko, Saji, Shigehira, Uemoto, Shinji, Asagiri, Masataka
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4208088/
https://ncbi.nlm.nih.gov/pubmed/25349782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fob.2014.08.007
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