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Necrostatin-1 protects against reactive oxygen species (ROS)-induced hepatotoxicity in acetaminophen-induced acute liver failure

Excessive acetaminophen (APAP) use is one of the most common causes of acute liver failure. Various types of cell death in the damaged liver are linked to APAP-induced hepatotoxicity, and, of these, necrotic cell death of hepatocytes has been shown to be involved in disease pathogenesis. Until recen...

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Hlavní autoři: Takemoto, Kenji, Hatano, Etsuro, Iwaisako, Keiko, Takeiri, Masatoshi, Noma, Naruto, Ohmae, Saori, Toriguchi, Kan, Tanabe, Kazutaka, Tanaka, Hirokazu, Seo, Satoru, Taura, Kojiro, Machida, Keigo, Takeda, Norihiko, Saji, Shigehira, Uemoto, Shinji, Asagiri, Masataka
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4208088/
https://ncbi.nlm.nih.gov/pubmed/25349782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fob.2014.08.007
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