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Osmotic Stress-induced Phosphorylation of H2AX by Polo-like Kinase 3 Affects Cell Cycle Progression in Human Corneal Epithelial Cells

Increased concentrations of extracellular solutes affect cell function and fate by stimulating cellular responses, such as evoking MAPK cascades, altering cell cycle progression, and causing apoptosis. Our study results here demonstrate that hyperosmotic stress induced H2AX phosphorylation (γH2AX) b...

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Bibliographische Detailangaben
Hauptverfasser: Wang, Ling, Dai, Wei, Lu, Luo
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4207995/
https://ncbi.nlm.nih.gov/pubmed/25202016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.597161
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