Increasing LH Pulsatility in Women With Hypothalamic Amenorrhoea Using Intravenous Infusion of Kisspeptin-54

BACKGROUND: Hypothalamic amenorrhea (HA) is the one of the most common causes of period loss in women of reproductive age and is associated with deficient LH pulsatility. High-dose kisspeptin-54 acutely stimulates LH secretion in women with HA, but chronic administration causes desensitization. GnRH...

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Main Authors: Jayasena, Channa N., Abbara, Ali, Veldhuis, Johannes D., Comninos, Alexander N., Ratnasabapathy, Risheka, De Silva, Akila, Nijher, Gurjinder M. K., Ganiyu-Dada, Zainab, Mehta, Amrish, Todd, Catriona, Ghatei, Mohammad A., Bloom, Stephen R., Dhillo, Waljit S.
格式: Artigo
語言:Inglês
出版: Endocrine Society 2014
主題:
Hot Topics in Translational Endocrinology
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4207927/
https://ncbi.nlm.nih.gov/pubmed/24517142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2013-1569
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