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The Tacrolimus Metabolism Rate Influences Renal Function after Kidney Transplantation

The effective calcineurin inhibitor (CNI) tacrolimus (Tac) is an integral part of the standard immunosuppressive regimen after renal transplantation (RTx). However, as a potent CNI it has nephrotoxic potential leading to impaired renal function in some cases. Therefore, it is of high clinical impact...

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Autors principals: Thölking, Gerold, Fortmann, Christian, Koch, Raphael, Gerth, Hans Ulrich, Pabst, Dirk, Pavenstädt, Hermann, Kabar, Iyad, Hüsing, Anna, Wolters, Heiner, Reuter, Stefan, Suwelack, Barbara
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4207775/
https://ncbi.nlm.nih.gov/pubmed/25340655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0111128
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