Disease specificity of kinase domains: the src-encoded catalytic domain converts erbB into a sarcoma oncogene.
src and erbB are two tyrosine kinase-encoding oncogenes carried by retroviruses, which have distinct disease specificities. The former induces predominantly sarcomas, and the latter, leukemias. Src and ErbB have similar catalytic domains but have very different regulatory domains. A wealth of inform...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
1995
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42075/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7732007/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.9.3928 |
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