Endoplasmic reticulum refilling and mitochondrial calcium extrusion promoted in neurons by NCX1 and NCX3 in ischemic preconditioning are determinant for neuroprotection

Ischemic preconditioning (IPC), an important endogenous adaptive mechanism of the CNS, renders the brain more tolerant to lethal cerebral ischemia. The molecular mechanisms responsible for the induction and maintenance of ischemic tolerance in the brain are complex and still remain undefined. Consid...

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Autors principals: Sisalli, M J, Secondo, A, Esposito, A, Valsecchi, V, Savoia, C, Di Renzo, G F, Annunziato, L, Scorziello, A
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2014
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Original Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4207481/
https://ncbi.nlm.nih.gov/pubmed/24632945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2014.32
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